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Primate cerebellar granule cells exhibit a tonic GABA(A)R conductance that is not affected by alcohol: a possible cellular substrate of the low level of response phenotype
In many rodent brain regions, alcohol increases vesicular release of GABA, resulting in an increase in the frequency of spontaneous inhibitory postsynaptic currents (sIPSCs) and the magnitude of tonic GABA(A) receptor (GABA(A)R) currents. A neglected issue in translating the rodent literature to hum...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840389/ https://www.ncbi.nlm.nih.gov/pubmed/24324408 http://dx.doi.org/10.3389/fncir.2013.00189 |