Primate cerebellar granule cells exhibit a tonic GABA(A)R conductance that is not affected by alcohol: a possible cellular substrate of the low level of response phenotype

In many rodent brain regions, alcohol increases vesicular release of GABA, resulting in an increase in the frequency of spontaneous inhibitory postsynaptic currents (sIPSCs) and the magnitude of tonic GABA(A) receptor (GABA(A)R) currents. A neglected issue in translating the rodent literature to hum...

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Detalles Bibliográficos
Autores principales: Mohr, Claudia, Kolotushkina, Olena, Kaplan, Joshua S., Welsh, John, Daunais, James B., Grant, Kathleen A., Rossi, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840389/
https://www.ncbi.nlm.nih.gov/pubmed/24324408
http://dx.doi.org/10.3389/fncir.2013.00189

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