NF-κB in T-cell Acute Lymphoblastic Leukemia: Oncogenic Functions in Leukemic and in Microenvironmental Cells

Two main NF-κB signaling pathways, canonical and noncanonical, performing distinct functions in organisms have been characterized. Identification of mutations in genes encoding components of these NF-κB signaling pathways in lymphoid malignancies confirmed their key role in leukemogenesis. T-cell ac...

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Detalles Bibliográficos
Autores principales: dos Santos, Nuno R., Ghezzo, Marinella N., da Silva, Ricardo C., Fernandes, Mónica T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840450/
https://www.ncbi.nlm.nih.gov/pubmed/24281204
http://dx.doi.org/10.3390/cancers2041838

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