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Nanoparticles in Sentinel Lymph Node Assessment in Breast Cancer

The modern management of the axilla in breast cancer relies on surgery for accurate staging of disease and identifying those patients at risk who would benefit from adjuvant chemotherapy. The introduction of sentinel lymph node biopsy has revolutionized axillary surgery, but still involves a surgica...

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Detalles Bibliográficos
Autores principales: Johnson, Laura, Charles-Edwards, Geoff, Douek, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840452/
https://www.ncbi.nlm.nih.gov/pubmed/24281206
http://dx.doi.org/10.3390/cancers2041884
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author Johnson, Laura
Charles-Edwards, Geoff
Douek, Michael
author_facet Johnson, Laura
Charles-Edwards, Geoff
Douek, Michael
author_sort Johnson, Laura
collection PubMed
description The modern management of the axilla in breast cancer relies on surgery for accurate staging of disease and identifying those patients at risk who would benefit from adjuvant chemotherapy. The introduction of sentinel lymph node biopsy has revolutionized axillary surgery, but still involves a surgical procedure with associated morbidity in many patients with no axillary involvement. Nanotechnology encompasses a broad spectrum of scientific specialities, of which nanomedicine is one. The potential use of dual-purpose nanoprobes could enable imaging the axilla simultaneous identification and treatment of metastatic disease. Whilst most applications of nanomedicine are still largely in the laboratory phase, some potential applications are currently undergoing clinical evaluation for translation from the bench to the bedside. This is an exciting new area of research where scientific research may become a reality.
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spelling pubmed-38404522013-11-26 Nanoparticles in Sentinel Lymph Node Assessment in Breast Cancer Johnson, Laura Charles-Edwards, Geoff Douek, Michael Cancers (Basel) Review The modern management of the axilla in breast cancer relies on surgery for accurate staging of disease and identifying those patients at risk who would benefit from adjuvant chemotherapy. The introduction of sentinel lymph node biopsy has revolutionized axillary surgery, but still involves a surgical procedure with associated morbidity in many patients with no axillary involvement. Nanotechnology encompasses a broad spectrum of scientific specialities, of which nanomedicine is one. The potential use of dual-purpose nanoprobes could enable imaging the axilla simultaneous identification and treatment of metastatic disease. Whilst most applications of nanomedicine are still largely in the laboratory phase, some potential applications are currently undergoing clinical evaluation for translation from the bench to the bedside. This is an exciting new area of research where scientific research may become a reality. MDPI 2010-11-17 /pmc/articles/PMC3840452/ /pubmed/24281206 http://dx.doi.org/10.3390/cancers2041884 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Johnson, Laura
Charles-Edwards, Geoff
Douek, Michael
Nanoparticles in Sentinel Lymph Node Assessment in Breast Cancer
title Nanoparticles in Sentinel Lymph Node Assessment in Breast Cancer
title_full Nanoparticles in Sentinel Lymph Node Assessment in Breast Cancer
title_fullStr Nanoparticles in Sentinel Lymph Node Assessment in Breast Cancer
title_full_unstemmed Nanoparticles in Sentinel Lymph Node Assessment in Breast Cancer
title_short Nanoparticles in Sentinel Lymph Node Assessment in Breast Cancer
title_sort nanoparticles in sentinel lymph node assessment in breast cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840452/
https://www.ncbi.nlm.nih.gov/pubmed/24281206
http://dx.doi.org/10.3390/cancers2041884
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