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Nanoparticles in Sentinel Lymph Node Assessment in Breast Cancer
The modern management of the axilla in breast cancer relies on surgery for accurate staging of disease and identifying those patients at risk who would benefit from adjuvant chemotherapy. The introduction of sentinel lymph node biopsy has revolutionized axillary surgery, but still involves a surgica...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840452/ https://www.ncbi.nlm.nih.gov/pubmed/24281206 http://dx.doi.org/10.3390/cancers2041884 |
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author | Johnson, Laura Charles-Edwards, Geoff Douek, Michael |
author_facet | Johnson, Laura Charles-Edwards, Geoff Douek, Michael |
author_sort | Johnson, Laura |
collection | PubMed |
description | The modern management of the axilla in breast cancer relies on surgery for accurate staging of disease and identifying those patients at risk who would benefit from adjuvant chemotherapy. The introduction of sentinel lymph node biopsy has revolutionized axillary surgery, but still involves a surgical procedure with associated morbidity in many patients with no axillary involvement. Nanotechnology encompasses a broad spectrum of scientific specialities, of which nanomedicine is one. The potential use of dual-purpose nanoprobes could enable imaging the axilla simultaneous identification and treatment of metastatic disease. Whilst most applications of nanomedicine are still largely in the laboratory phase, some potential applications are currently undergoing clinical evaluation for translation from the bench to the bedside. This is an exciting new area of research where scientific research may become a reality. |
format | Online Article Text |
id | pubmed-3840452 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-38404522013-11-26 Nanoparticles in Sentinel Lymph Node Assessment in Breast Cancer Johnson, Laura Charles-Edwards, Geoff Douek, Michael Cancers (Basel) Review The modern management of the axilla in breast cancer relies on surgery for accurate staging of disease and identifying those patients at risk who would benefit from adjuvant chemotherapy. The introduction of sentinel lymph node biopsy has revolutionized axillary surgery, but still involves a surgical procedure with associated morbidity in many patients with no axillary involvement. Nanotechnology encompasses a broad spectrum of scientific specialities, of which nanomedicine is one. The potential use of dual-purpose nanoprobes could enable imaging the axilla simultaneous identification and treatment of metastatic disease. Whilst most applications of nanomedicine are still largely in the laboratory phase, some potential applications are currently undergoing clinical evaluation for translation from the bench to the bedside. This is an exciting new area of research where scientific research may become a reality. MDPI 2010-11-17 /pmc/articles/PMC3840452/ /pubmed/24281206 http://dx.doi.org/10.3390/cancers2041884 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Johnson, Laura Charles-Edwards, Geoff Douek, Michael Nanoparticles in Sentinel Lymph Node Assessment in Breast Cancer |
title | Nanoparticles in Sentinel Lymph Node Assessment in Breast Cancer |
title_full | Nanoparticles in Sentinel Lymph Node Assessment in Breast Cancer |
title_fullStr | Nanoparticles in Sentinel Lymph Node Assessment in Breast Cancer |
title_full_unstemmed | Nanoparticles in Sentinel Lymph Node Assessment in Breast Cancer |
title_short | Nanoparticles in Sentinel Lymph Node Assessment in Breast Cancer |
title_sort | nanoparticles in sentinel lymph node assessment in breast cancer |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840452/ https://www.ncbi.nlm.nih.gov/pubmed/24281206 http://dx.doi.org/10.3390/cancers2041884 |
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