Pigment epithelium-derived factor reduces apoptosis and pro-inflammatory cytokine gene expression in a murine model of focal retinal degeneration

AMD (age-related macular degeneration) is a neurodegenerative disease causing irreversible central blindness in the elderly. Apoptosis and inflammation play important roles in AMD pathogenesis. PEDF (pigment epithelium-derived factor) is a potent neurotrophic and anti-inflammatory glycoprotein that...

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Detalles Bibliográficos
Autores principales: Wang, Yujuan, Subramanian, Preeti, Shen, Defen, Tuo, Jingsheng, Becerra, S. Patricia, Chan, Chi-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840469/
https://www.ncbi.nlm.nih.gov/pubmed/24160756
http://dx.doi.org/10.1042/AN20130028

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