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Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK
The p38 MAPK pathway is an important regulator of many cellular responses. It is well established that p38 MAPK signalling negatively regulates epithelial cell transformation, but enhanced p38 MAPK activity has been also correlated with bad clinical prognosis in some tumour types. Here, we provide g...
Autores principales: | Pereira, Lorena, Igea, Ana, Canovas, Begoña, Dolado, Ignacio, Nebreda, Angel R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840490/ https://www.ncbi.nlm.nih.gov/pubmed/24115572 http://dx.doi.org/10.1002/emmm.201302732 |
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