Novel Variants of Clade 2.3.4 Highly Pathogenic Avian Influenza A(H5N1) Viruses, China

We characterized 7 highly pathogenic avian influenza A(H5N1) viruses isolated from poultry in China during 2009–2012 and found that they belong to clade 2.3.4 but do not fit within the 3 defined subclades. Antigenic drift in subtype H5N1 variants may reduce the efficacy of vaccines designed to contr...

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Detalles Bibliográficos
Autores principales: Gu, Min, Zhao, Guo, Zhao, Kunkun, Zhong, Lei, Huang, Junqing, Wan, Hongquan, Wang, Xiaoquan, Liu, Wenbo, Liu, Huimou, Peng, Daxin, Liu, Xiufan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2013
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840869/
https://www.ncbi.nlm.nih.gov/pubmed/24274396
http://dx.doi.org/10.3201/eid1912.130340
Descripción
Sumario:We characterized 7 highly pathogenic avian influenza A(H5N1) viruses isolated from poultry in China during 2009–2012 and found that they belong to clade 2.3.4 but do not fit within the 3 defined subclades. Antigenic drift in subtype H5N1 variants may reduce the efficacy of vaccines designed to control these viruses in poultry.

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