Novel Variants of Clade 2.3.4 Highly Pathogenic Avian Influenza A(H5N1) Viruses, China

We characterized 7 highly pathogenic avian influenza A(H5N1) viruses isolated from poultry in China during 2009–2012 and found that they belong to clade 2.3.4 but do not fit within the 3 defined subclades. Antigenic drift in subtype H5N1 variants may reduce the efficacy of vaccines designed to contr...

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Autores principales: Gu, Min, Zhao, Guo, Zhao, Kunkun, Zhong, Lei, Huang, Junqing, Wan, Hongquan, Wang, Xiaoquan, Liu, Wenbo, Liu, Huimou, Peng, Daxin, Liu, Xiufan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2013
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840869/
https://www.ncbi.nlm.nih.gov/pubmed/24274396
http://dx.doi.org/10.3201/eid1912.130340
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author Gu, Min
Zhao, Guo
Zhao, Kunkun
Zhong, Lei
Huang, Junqing
Wan, Hongquan
Wang, Xiaoquan
Liu, Wenbo
Liu, Huimou
Peng, Daxin
Liu, Xiufan
author_facet Gu, Min
Zhao, Guo
Zhao, Kunkun
Zhong, Lei
Huang, Junqing
Wan, Hongquan
Wang, Xiaoquan
Liu, Wenbo
Liu, Huimou
Peng, Daxin
Liu, Xiufan
author_sort Gu, Min
collection PubMed
description We characterized 7 highly pathogenic avian influenza A(H5N1) viruses isolated from poultry in China during 2009–2012 and found that they belong to clade 2.3.4 but do not fit within the 3 defined subclades. Antigenic drift in subtype H5N1 variants may reduce the efficacy of vaccines designed to control these viruses in poultry.
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spelling pubmed-38408692013-12-04 Novel Variants of Clade 2.3.4 Highly Pathogenic Avian Influenza A(H5N1) Viruses, China Gu, Min Zhao, Guo Zhao, Kunkun Zhong, Lei Huang, Junqing Wan, Hongquan Wang, Xiaoquan Liu, Wenbo Liu, Huimou Peng, Daxin Liu, Xiufan Emerg Infect Dis Dispatch We characterized 7 highly pathogenic avian influenza A(H5N1) viruses isolated from poultry in China during 2009–2012 and found that they belong to clade 2.3.4 but do not fit within the 3 defined subclades. Antigenic drift in subtype H5N1 variants may reduce the efficacy of vaccines designed to control these viruses in poultry. Centers for Disease Control and Prevention 2013-12 /pmc/articles/PMC3840869/ /pubmed/24274396 http://dx.doi.org/10.3201/eid1912.130340 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Gu, Min
Zhao, Guo
Zhao, Kunkun
Zhong, Lei
Huang, Junqing
Wan, Hongquan
Wang, Xiaoquan
Liu, Wenbo
Liu, Huimou
Peng, Daxin
Liu, Xiufan
Novel Variants of Clade 2.3.4 Highly Pathogenic Avian Influenza A(H5N1) Viruses, China
title Novel Variants of Clade 2.3.4 Highly Pathogenic Avian Influenza A(H5N1) Viruses, China
title_full Novel Variants of Clade 2.3.4 Highly Pathogenic Avian Influenza A(H5N1) Viruses, China
title_fullStr Novel Variants of Clade 2.3.4 Highly Pathogenic Avian Influenza A(H5N1) Viruses, China
title_full_unstemmed Novel Variants of Clade 2.3.4 Highly Pathogenic Avian Influenza A(H5N1) Viruses, China
title_short Novel Variants of Clade 2.3.4 Highly Pathogenic Avian Influenza A(H5N1) Viruses, China
title_sort novel variants of clade 2.3.4 highly pathogenic avian influenza a(h5n1) viruses, china
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840869/
https://www.ncbi.nlm.nih.gov/pubmed/24274396
http://dx.doi.org/10.3201/eid1912.130340
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