Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia

We used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS...

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Detalles Bibliográficos
Autores principales: Gierer, Stefanie, Hofmann-Winkler, Heike, Albuali, Waleed H., Bertram, Stephanie, Al-Rubaish, Abdullah M., Yousef, Abdullah A., Al-Nafaie, Awatif N., Al-Ali, Amein K., Obeid, Obeid E., Alkharsah, Khaled R., Pöhlmann, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2013
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840893/
https://www.ncbi.nlm.nih.gov/pubmed/24274664
http://dx.doi.org/10.3201/eid1912.130701
Descripción
Sumario:We used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS-CoV infections in humans are infrequent in this province.

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