Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia

We used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS...

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Autores principales: Gierer, Stefanie, Hofmann-Winkler, Heike, Albuali, Waleed H., Bertram, Stephanie, Al-Rubaish, Abdullah M., Yousef, Abdullah A., Al-Nafaie, Awatif N., Al-Ali, Amein K., Obeid, Obeid E., Alkharsah, Khaled R., Pöhlmann, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2013
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840893/
https://www.ncbi.nlm.nih.gov/pubmed/24274664
http://dx.doi.org/10.3201/eid1912.130701
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author Gierer, Stefanie
Hofmann-Winkler, Heike
Albuali, Waleed H.
Bertram, Stephanie
Al-Rubaish, Abdullah M.
Yousef, Abdullah A.
Al-Nafaie, Awatif N.
Al-Ali, Amein K.
Obeid, Obeid E.
Alkharsah, Khaled R.
Pöhlmann, Stefan
author_facet Gierer, Stefanie
Hofmann-Winkler, Heike
Albuali, Waleed H.
Bertram, Stephanie
Al-Rubaish, Abdullah M.
Yousef, Abdullah A.
Al-Nafaie, Awatif N.
Al-Ali, Amein K.
Obeid, Obeid E.
Alkharsah, Khaled R.
Pöhlmann, Stefan
author_sort Gierer, Stefanie
collection PubMed
description We used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS-CoV infections in humans are infrequent in this province.
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spelling pubmed-38408932013-12-04 Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia Gierer, Stefanie Hofmann-Winkler, Heike Albuali, Waleed H. Bertram, Stephanie Al-Rubaish, Abdullah M. Yousef, Abdullah A. Al-Nafaie, Awatif N. Al-Ali, Amein K. Obeid, Obeid E. Alkharsah, Khaled R. Pöhlmann, Stefan Emerg Infect Dis Dispatch We used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS-CoV infections in humans are infrequent in this province. Centers for Disease Control and Prevention 2013-12 /pmc/articles/PMC3840893/ /pubmed/24274664 http://dx.doi.org/10.3201/eid1912.130701 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Gierer, Stefanie
Hofmann-Winkler, Heike
Albuali, Waleed H.
Bertram, Stephanie
Al-Rubaish, Abdullah M.
Yousef, Abdullah A.
Al-Nafaie, Awatif N.
Al-Ali, Amein K.
Obeid, Obeid E.
Alkharsah, Khaled R.
Pöhlmann, Stefan
Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia
title Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia
title_full Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia
title_fullStr Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia
title_full_unstemmed Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia
title_short Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia
title_sort lack of mers coronavirus neutralizing antibodies in humans, eastern province, saudi arabia
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840893/
https://www.ncbi.nlm.nih.gov/pubmed/24274664
http://dx.doi.org/10.3201/eid1912.130701
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