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Binding of the auxiliary subunit TRIP8b to HCN channels shifts the mode of action of cAMP

Hyperpolarization-activated cyclic nucleotide–regulated cation (HCN) channels generate the hyperpolarization-activated cation current Ih present in many neurons. These channels are directly regulated by the binding of cAMP, which both shifts the voltage dependence of HCN channel opening to more posi...

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Detalles Bibliográficos
Autores principales:	Hu, Lei, Santoro, Bina, Saponaro, Andrea, Liu, Haiying, Moroni, Anna, Siegelbaum, Steven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840918/ https://www.ncbi.nlm.nih.gov/pubmed/24277603 http://dx.doi.org/10.1085/jgp.201311013

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