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The gating charge should not be estimated by fitting a two-state model to a Q-V curve

The voltage dependence of charges in voltage-sensitive proteins, typically displayed as charge versus voltage (Q-V) curves, is often quantified by fitting it to a simple two-state Boltzmann function. This procedure overlooks the fact that the fitted parameters, including the total charge, may be inc...

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Detalles Bibliográficos
Autores principales: Bezanilla, Francisco, Villalba-Galea, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840919/
https://www.ncbi.nlm.nih.gov/pubmed/24218396
http://dx.doi.org/10.1085/jgp.201311056

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