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The gating charge should not be estimated by fitting a two-state model to a Q-V curve
The voltage dependence of charges in voltage-sensitive proteins, typically displayed as charge versus voltage (Q-V) curves, is often quantified by fitting it to a simple two-state Boltzmann function. This procedure overlooks the fact that the fitted parameters, including the total charge, may be inc...
Autores principales: | Bezanilla, Francisco, Villalba-Galea, Carlos A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840919/ https://www.ncbi.nlm.nih.gov/pubmed/24218396 http://dx.doi.org/10.1085/jgp.201311056 |
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