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Peregrination of the selectivity filter delineates the pore of the human voltage-gated proton channel hH(V)1
Extraordinary selectivity is crucial to all proton-conducting molecules, including the human voltage-gated proton channel (hH(V)1), because the proton concentration is >10(6) times lower than that of other cations. Here we use “selectivity filter scanning” to elucidate the molecular requirements...
Autores principales: | Morgan, Deri, Musset, Boris, Kulleperuma, Kethika, Smith, Susan M.E., Rajan, Sindhu, Cherny, Vladimir V., Pomès, Régis, DeCoursey, Thomas E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840923/ https://www.ncbi.nlm.nih.gov/pubmed/24218398 http://dx.doi.org/10.1085/jgp.201311045 |
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