Atrophin–Rpd3 complex represses Hedgehog signaling by acting as a corepressor of Ci(R)

The evolutionarily conserved Hedgehog (Hh) signaling pathway is transduced by the Cubitus interruptus (Ci)/Gli family of transcription factors that exist in two distinct repressor (Ci(R)/Gli(R)) and activator (Ci(A)/Gli(A)) forms. Aberrant activation of Hh signaling is associated with various human...

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Detalles Bibliográficos
Autores principales: Zhang, Zhao, Feng, Jing, Pan, Chenyu, Lv, Xiangdong, Wu, Wenqing, Zhou, Zhaocai, Liu, Feng, Zhang, Lei, Zhao, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840934/
https://www.ncbi.nlm.nih.gov/pubmed/24385484
http://dx.doi.org/10.1083/jcb.201306012

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