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Two phases of disulfide bond formation have differing requirements for oxygen

Most proteins destined for the extracellular space require disulfide bonds for folding and stability. Disulfide bonds are introduced co- and post-translationally in endoplasmic reticulum (ER) cargo in a redox relay that requires a terminal electron acceptor. Oxygen can serve as the electron acceptor...

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Detalles Bibliográficos
Autores principales:	Koritzinsky, Marianne, Levitin, Fiana, van den Beucken, Twan, Rumantir, Ryan A., Harding, Nicholas J., Chu, Kenneth C., Boutros, Paul C., Braakman, Ineke, Wouters, Bradly G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840938/ https://www.ncbi.nlm.nih.gov/pubmed/24247433 http://dx.doi.org/10.1083/jcb.201307185

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