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WNT3 Inhibits Cerebellar Granule Neuron Progenitor Proliferation and Medulloblastoma Formation via MAPK Activation

During normal cerebellar development, the remarkable expansion of granule cell progenitors (GCPs) generates a population of granule neurons that outnumbers the total neuronal population of the cerebral cortex, and provides a model for identifying signaling pathways that may be defective in medullobl...

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Detalles Bibliográficos
Autores principales:	Anne, Sandrine L., Govek, Eve-Ellen, Ayrault, Olivier, Kim, Jee Hae, Zhu, Xiaodong, Murphy, David A., Van Aelst, Linda, Roussel, Martine F., Hatten, Mary E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841149/ https://www.ncbi.nlm.nih.gov/pubmed/24303070 http://dx.doi.org/10.1371/journal.pone.0081769

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