Leishmania braziliensis-Reactive T Cells Are Down-Regulated in Long-Term Cured Cutaneous Leishmaniasis, but the Renewal Capacity of T Effector Memory Compartments Is Preserved

Leishmania (Viannia) braziliensis control and tissue damage relate to the effector immune response, which in turn affects clinical outcome. Leishmania reactive CD4(+) and CD8(+) T cells are expanded in long-term healed cutaneous leishmaniasis (hCL) patients but their functional characteristics remai...

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Detalles Bibliográficos
Autores principales: Pereira-Carvalho, Regina, Mendes-Aguiar, Carolina O., Oliveira-Neto, Manoel P., Covas, Cláudia J. F., Bertho, Álvaro L., Da-Cruz, Alda M., Gomes-Silva, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841203/
https://www.ncbi.nlm.nih.gov/pubmed/24303052
http://dx.doi.org/10.1371/journal.pone.0081529

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