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Rapamycin regulates biochemical metabolites
The mammalian target of rapamycin (mTOR) kinase is a master regulator of protein synthesis that couples nutrient sensing to cell growth, and deregulation of this pathway is associated with tumorigenesis. p53, and its less investigated family member p73, have been shown to interact closely with mTOR...
Autores principales: | Tucci, Paola, Porta, Giovanni, Agostini, Massimiliano, Antonov, Alexey, Garabadgiu, Alexander Vasilievich, Melino, Gerry, Willis, Anne E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841324/ https://www.ncbi.nlm.nih.gov/pubmed/23839040 http://dx.doi.org/10.4161/cc.25450 |
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