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p53 mutations associated with aging-related rise in cancer incidence rates
TP53’s role as guardian of the genome diminishes with age, as the probability of mutation increases. Previous studies have shown an association between p53 gene mutations and cancer. However, the role of somatic TP53 mutations in the steep rise in cancer rates with aging has not been investigated at...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841325/ https://www.ncbi.nlm.nih.gov/pubmed/23839036 http://dx.doi.org/10.4161/cc.25494 |