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Accidental phosgene gas exposure: A review with background study of 10 cases

Here, authors present a review on clinical presentation and management of exposure of phosgene gas after reviewing the literature by searching with keywords phosgene exposure on Google, Cochrane, Embase and PubMed with a background of experience gained from 10 patients who were admitted to our insti...

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Autores principales: Vaish, Arvind Kumar, Consul, Shuchi, Agrawal, Avinash, Chaudhary, Shyam Chand, Gutch, Manish, Jain, Nirdesh, Singh, Mohit Mohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841534/
https://www.ncbi.nlm.nih.gov/pubmed/24339660
http://dx.doi.org/10.4103/0974-2700.120372
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author Vaish, Arvind Kumar
Consul, Shuchi
Agrawal, Avinash
Chaudhary, Shyam Chand
Gutch, Manish
Jain, Nirdesh
Singh, Mohit Mohan
author_facet Vaish, Arvind Kumar
Consul, Shuchi
Agrawal, Avinash
Chaudhary, Shyam Chand
Gutch, Manish
Jain, Nirdesh
Singh, Mohit Mohan
author_sort Vaish, Arvind Kumar
collection PubMed
description Here, authors present a review on clinical presentation and management of exposure of phosgene gas after reviewing the literature by searching with keywords phosgene exposure on Google, Cochrane, Embase and PubMed with a background of experience gained from 10 patients who were admitted to our institute after an accidental phosgene exposure in February 2011 nearby a city in India. Phosgene is a highly toxic gas, occupational workers may have accidental exposure. The gas can also be generated inadvertently during fire involving plastics and other chemicals and solvents containing chlorine, which is of concern to emergency responders. Phosgene inhalation may cause initially symptoms of respiratory tract irritation, patients feel fine thereafter, and then die of choking a day later because of build up of fluid in the lungs (delayed onset non-cardiogenic pulmonary edema). Phosgene exposure is associated with significant morbidity and mortality. Patients with a history of exposure should be admitted to the hospital for a minimum of 24 h for observation because of the potential for delayed onset respiratory failure and acute respiratory distress syndrome.
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spelling pubmed-38415342013-12-11 Accidental phosgene gas exposure: A review with background study of 10 cases Vaish, Arvind Kumar Consul, Shuchi Agrawal, Avinash Chaudhary, Shyam Chand Gutch, Manish Jain, Nirdesh Singh, Mohit Mohan J Emerg Trauma Shock Review Article Here, authors present a review on clinical presentation and management of exposure of phosgene gas after reviewing the literature by searching with keywords phosgene exposure on Google, Cochrane, Embase and PubMed with a background of experience gained from 10 patients who were admitted to our institute after an accidental phosgene exposure in February 2011 nearby a city in India. Phosgene is a highly toxic gas, occupational workers may have accidental exposure. The gas can also be generated inadvertently during fire involving plastics and other chemicals and solvents containing chlorine, which is of concern to emergency responders. Phosgene inhalation may cause initially symptoms of respiratory tract irritation, patients feel fine thereafter, and then die of choking a day later because of build up of fluid in the lungs (delayed onset non-cardiogenic pulmonary edema). Phosgene exposure is associated with significant morbidity and mortality. Patients with a history of exposure should be admitted to the hospital for a minimum of 24 h for observation because of the potential for delayed onset respiratory failure and acute respiratory distress syndrome. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3841534/ /pubmed/24339660 http://dx.doi.org/10.4103/0974-2700.120372 Text en Copyright: © Journal of Emergencies, Trauma, and Shock http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Vaish, Arvind Kumar
Consul, Shuchi
Agrawal, Avinash
Chaudhary, Shyam Chand
Gutch, Manish
Jain, Nirdesh
Singh, Mohit Mohan
Accidental phosgene gas exposure: A review with background study of 10 cases
title Accidental phosgene gas exposure: A review with background study of 10 cases
title_full Accidental phosgene gas exposure: A review with background study of 10 cases
title_fullStr Accidental phosgene gas exposure: A review with background study of 10 cases
title_full_unstemmed Accidental phosgene gas exposure: A review with background study of 10 cases
title_short Accidental phosgene gas exposure: A review with background study of 10 cases
title_sort accidental phosgene gas exposure: a review with background study of 10 cases
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841534/
https://www.ncbi.nlm.nih.gov/pubmed/24339660
http://dx.doi.org/10.4103/0974-2700.120372
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