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No CAG repeat expansion of polymerase gamma is associated with male infertility in Tamil Nadu, South India
Mitochondria contains a single deoxyribonucleic acid (DNA) polymerase, polymerase gamma (POLG) mapped to long arm of chromosome 15 (15q25), responsible for replication and repair of mitochondrial DNA. Exon 1 of the human POLG contains CAG trinucleotide repeat, which codes for polyglutamate. Ten copi...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841557/ https://www.ncbi.nlm.nih.gov/pubmed/24339545 http://dx.doi.org/10.4103/0971-6866.120823 |