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Voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child: A case report and literature review of an under-recognized condition

Autoimmune limbic encephalitis (LE) associated with voltage gated potassium channel antibodies (VGKC-Abs) in children is more common than previously thought and is not always paraneoplastic. Non-neoplastic, autoimmune LE associated with VGKC-Abs has been described recently. However, only few case re...

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Autores principales: Ganesan, Subramanian, Beri, Sushil, Khan, Beri, Hussain, Nahin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841607/
https://www.ncbi.nlm.nih.gov/pubmed/24339586
http://dx.doi.org/10.4103/0972-2327.120483
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author Ganesan, Subramanian
Beri, Sushil
Khan, Beri
Hussain, Nahin
author_facet Ganesan, Subramanian
Beri, Sushil
Khan, Beri
Hussain, Nahin
author_sort Ganesan, Subramanian
collection PubMed
description Autoimmune limbic encephalitis (LE) associated with voltage gated potassium channel antibodies (VGKC-Abs) in children is more common than previously thought and is not always paraneoplastic. Non-neoplastic, autoimmune LE associated with VGKC-Abs has been described recently. However, only few case reports in children as the disease is predominantly described in the adult population. It is likely that this type of autoimmune encephalitis is currently under-diagnosed and hence, under-treated, especially in children. We present a 13-year-old previously fit and healthy African girl diagnosed with LE and we reviewed the literature for its current management.
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spelling pubmed-38416072013-12-11 Voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child: A case report and literature review of an under-recognized condition Ganesan, Subramanian Beri, Sushil Khan, Beri Hussain, Nahin Ann Indian Acad Neurol Case Report Autoimmune limbic encephalitis (LE) associated with voltage gated potassium channel antibodies (VGKC-Abs) in children is more common than previously thought and is not always paraneoplastic. Non-neoplastic, autoimmune LE associated with VGKC-Abs has been described recently. However, only few case reports in children as the disease is predominantly described in the adult population. It is likely that this type of autoimmune encephalitis is currently under-diagnosed and hence, under-treated, especially in children. We present a 13-year-old previously fit and healthy African girl diagnosed with LE and we reviewed the literature for its current management. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3841607/ /pubmed/24339586 http://dx.doi.org/10.4103/0972-2327.120483 Text en Copyright: © Annals of Indian Academy of Neurology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ganesan, Subramanian
Beri, Sushil
Khan, Beri
Hussain, Nahin
Voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child: A case report and literature review of an under-recognized condition
title Voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child: A case report and literature review of an under-recognized condition
title_full Voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child: A case report and literature review of an under-recognized condition
title_fullStr Voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child: A case report and literature review of an under-recognized condition
title_full_unstemmed Voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child: A case report and literature review of an under-recognized condition
title_short Voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child: A case report and literature review of an under-recognized condition
title_sort voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child: a case report and literature review of an under-recognized condition
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841607/
https://www.ncbi.nlm.nih.gov/pubmed/24339586
http://dx.doi.org/10.4103/0972-2327.120483
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