Cargando…
Inhibitory Receptor Signaling Destabilizes Immunological Synapse Formation in Primary NK Cells
Upon engagement of their cognate class I major histocompatibility complex ligands, receptors containing immunotyrosine-based inhibitory motifs (ITIMs) transduce signals that block cytolytic and inflammatory responses. In this manner, ITIM-coupled receptors play a crucial role in maintaining natural...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841721/ https://www.ncbi.nlm.nih.gov/pubmed/24348477 http://dx.doi.org/10.3389/fimmu.2013.00410 |