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Inhibitory Receptor Signaling Destabilizes Immunological Synapse Formation in Primary NK Cells

Upon engagement of their cognate class I major histocompatibility complex ligands, receptors containing immunotyrosine-based inhibitory motifs (ITIMs) transduce signals that block cytolytic and inflammatory responses. In this manner, ITIM-coupled receptors play a crucial role in maintaining natural...

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Detalles Bibliográficos
Autores principales:	Abeyweera, Thushara P., Kaissar, Molly, Huse, Morgan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841721/ https://www.ncbi.nlm.nih.gov/pubmed/24348477 http://dx.doi.org/10.3389/fimmu.2013.00410

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