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Elimination of shelterin components bypasses RNAi for pericentric heterochromatin assembly

The RNAi pathway is required for heterochromatin assembly at repetitive DNA elements in diverse organisms. In fission yeast, loss of RNAi causes pericentric heterochromatin defects, compromising gene silencing and chromosome segregation. Here we show that deletion of telomere shelterin components re...

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Detalles Bibliográficos
Autores principales: Tadeo, Xavier, Wang, Jiyong, Kallgren, Scott P., Liu, Jinqiang, Reddy, Bharat D., Qiao, Feng, Jia, Songtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841737/
https://www.ncbi.nlm.nih.gov/pubmed/24240238
http://dx.doi.org/10.1101/gad.226118.113