Beyond DNA Repair: Additional Functions of PARP-1 in Cancer

Poly(ADP-ribose) polymerases (PARPs) are DNA-dependent nuclear enzymes that transfer negatively charged ADP-ribose moieties from cellular nicotinamide-adenine-dinucleotide (NAD(+)) to a variety of protein substrates, altering protein–protein and protein-DNA interactions. The most studied of these en...

Descripción completa

Detalles Bibliográficos
Autores principales: Weaver, Alice N., Yang, Eddy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841914/
https://www.ncbi.nlm.nih.gov/pubmed/24350055
http://dx.doi.org/10.3389/fonc.2013.00290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841914/
https://www.ncbi.nlm.nih.gov/pubmed/24350055
http://dx.doi.org/10.3389/fonc.2013.00290

Ejemplares similares