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Conditional Dicer Substrate Formation via Shape and Sequence Transduction with Small Conditional RNAs
[Image: see text] RNA interference (RNAi) mediated by small interfering RNAs (siRNAs) enables knockdown of a gene of choice, executing the logical operation: silence gene Y. The fact that the siRNA is constitutively active is a significant limitation, making it difficult to confine knockdown to a sp...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842090/ https://www.ncbi.nlm.nih.gov/pubmed/24219616 http://dx.doi.org/10.1021/ja404676x |