Cargando…
Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital
Acetaminophen overdose is a common reason for hospital admission and the most frequent cause of hepatotoxicity in the Western world. Early identification would facilitate patient-individualized treatment strategies. We investigated the potential of a panel of novel biomarkers (with enhanced liver ex...
Autores principales: | Antoine, Daniel J, Dear, James W, Lewis, Philip Starkey, Platt, Vivien, Coyle, Judy, Masson, Moyra, Thanacoody, Ruben H, Gray, Alasdair J, Webb, David J, Moggs, Jonathan G, Bateman, D Nicholas, Goldring, Christopher E, Park, B Kevin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842113/ https://www.ncbi.nlm.nih.gov/pubmed/23390034 http://dx.doi.org/10.1002/hep.26294 |
Ejemplares similares
-
Circulating Kidney Injury Molecule 1 Predicts Prognosis and Poor Outcome in Patients With Acetaminophen‐Induced Liver Injury
por: Antoine, Daniel J., et al.
Publicado: (2015) -
A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug‐induced liver injury and postinjury inflammation in mice
por: Lundbäck, Peter, et al.
Publicado: (2016) -
Hepatic Histological Findings in Suspected Drug-Induced Liver Injury: Systematic Evaluation and Clinical Associations
por: Kleiner, David E, et al.
Publicado: (2014) -
Yes-Associated Protein Regulates the Hepatic Response After Bile Duct Ligation
por: Bai, Haibo, et al.
Publicado: (2012) -
Endogenous Histones Function as Alarmins in Sterile Inflammatory Liver Injury Through Toll-like Receptor 9 in Mice
por: Huang, Hai, et al.
Publicado: (2011)