The principal PINK1 and Parkin cellular events triggered in response to dissipation of mitochondrial membrane potential occur in primary neurons

PINK1 and PARKIN are causal genes for hereditary Parkinsonism. Recent studies have shown that PINK1 and Parkin play a pivotal role in the quality control of mitochondria, and dysfunction of either protein likely results in the accumulation of low-quality mitochondria that triggers early-onset famili...

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Detalles Bibliográficos
Autores principales: Koyano, Fumika, Okatsu, Kei, Ishigaki, Shinsuke, Fujioka, Yusuke, Kimura, Mayumi, Sobue, Gen, Tanaka, Keiji, Matsuda, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842116/
https://www.ncbi.nlm.nih.gov/pubmed/23751051
http://dx.doi.org/10.1111/gtc.12066

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