Cargando…

Carcinoma cells misuse the host tissue damage response to invade the brain

The metastatic colonization of the brain by carcinoma cells is still barely understood, in particular when considering interactions with the host tissue. The colonization comes with a substantial destruction of the surrounding host tissue. This leads to activation of damage responses by resident inn...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chuang, Han-Ning, van Rossum, Denise, Sieger, Dirk, Siam, Laila, Klemm, Florian, Bleckmann, Annalen, Bayerlová, Michaela, Farhat, Katja, Scheffel, Jörg, Schulz, Matthias, Dehghani, Faramarz, Stadelmann, Christine, Hanisch, Uwe-Karsten, Binder, Claudia, Pukrop, Tobias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842117/ https://www.ncbi.nlm.nih.gov/pubmed/23832647 http://dx.doi.org/10.1002/glia.22518

Ejemplares similares

Newly Constructed Network Models of Different WNT Signaling Cascades Applied to Breast Cancer Expression Data
por: Bayerlová, Michaela, et al.
Publicado: (2015)

Anti-CSF-1 treatment is effective to prevent carcinoma invasion induced by monocyte-derived cells but scarcely by microglia
por: Rietkötter, Eva, et al.
Publicado: (2015)

Ror2 Signaling and Its Relevance in Breast Cancer Progression
por: Bayerlová, Michaela, et al.
Publicado: (2017)

Zoledronic acid inhibits macrophage/microglia-assisted breast cancer cell invasion
por: Rietkötter, Eva, et al.
Publicado: (2013)

Coculture System with an Organotypic Brain Slice and 3D Spheroid of Carcinoma Cells
por: Chuang, Han-Ning, et al.
Publicado: (2013)

Comparative study on gene set and pathway topology-based enrichment methods
por: Bayerlová, Michaela, et al.
Publicado: (2015)

Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN
por: Menck, Kerstin, et al.
Publicado: (2015)

Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear β-catenin in cerebral metastasis of lung adenocarcinomas
por: Bleckmann, A., et al.
Publicado: (2012)

The metastatic infiltration at the metastasis/brain parenchyma-interface is very heterogeneous and has a significant impact on survival in a prospective study
por: Siam, Laila, et al.
Publicado: (2015)

5-Aminolevulinic Acid Fluorescence Indicates Perilesional Brain Infiltration in Brain Metastases
por: Schatlo, Bawarjan, et al.
Publicado: (2019)

Integrated miRNA and mRNA profiling of tumor‐educated macrophages identifies prognostic subgroups in estrogen receptor‐positive breast cancer
por: Bleckmann, Annalen, et al.
Publicado: (2014)

Intralesional TLR4 agonist treatment strengthens the organ defense against colonizing cancer cells in the brain
por: Blazquez, Raquel, et al.
Publicado: (2022)

Characterisation of tumour-derived microvesicles in cancer patients’ blood and correlation with clinical outcome
por: Menck, Kerstin, et al.
Publicado: (2017)

Relaxins enhance growth of spontaneous murine breast cancers as well as metastatic colonization of the brain
por: Binder, Claudia, et al.
Publicado: (2013)

Isolation and Characterization of Microvesicles from Peripheral Blood
por: Menck, Kerstin, et al.
Publicado: (2017)

Microvesicles in Cancer: Small Size, Large Potential
por: Menck, Kerstin, et al.
Publicado: (2020)

β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases
por: Bleckmann, Annalen, et al.
Publicado: (2016)

Impact of pre-OP independence in patients with limited brain metastases on long-term survival
por: Bleckmann, Annalen, et al.
Publicado: (2020)

Isolated metastasis of an EGFR-L858R-mutated NSCLC of the meninges: the potential impact of CXCL12/CXCR4 axis in EGFR(mut) NSCLC in diagnosis, follow-up and treatment
por: Lüke, Florian, et al.
Publicado: (2018)

WNT11/ROR2 signaling is associated with tumor invasion and poor survival in breast cancer
por: Menck, Kerstin, et al.
Publicado: (2021)

Metabolomic Profiling of Blood-Derived Microvesicles in Breast Cancer Patients
por: Buentzel, Judith, et al.
Publicado: (2021)

Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles
por: Menck, Kerstin, et al.
Publicado: (2013)

Extracellular vesicle-associated tyrosine kinase-like orphan receptors ROR1 and ROR2 promote breast cancer progression
por: Irmer, Barnabas, et al.
Publicado: (2023)

Coordination of Tongue Activity During Swallowing in Mouth-breathing Children
por: Knösel, Michael, et al.
Publicado: (2011)

Detection of Simultaneous Group Effects in MicroRNA Expression and Related Target Gene Sets
por: Artmann, Stephan, et al.
Publicado: (2012)

The WNT/ROR Pathway in Cancer: From Signaling to Therapeutic Intervention
por: Menck, Kerstin, et al.
Publicado: (2021)

Isolation of Human Monocytes by Double Gradient Centrifugation and Their Differentiation to Macrophages in Teflon-coated Cell Culture Bags
por: Menck, Kerstin, et al.
Publicado: (2014)

Predicting restoration of kidney function during CRRT-free intervals
por: Heise, Daniel, et al.
Publicado: (2012)

To treat or not to treat: A rare case of response to pembrolizumab‐based immunotherapy‐chemotherapy in non‐small cell lung cancer with acute liver failure due to multiple bile duct metastases
por: Shaforostova, Inna, et al.
Publicado: (2020)

Extracellular Vesicles in Liquid Biopsies as Biomarkers for Solid Tumors
por: Irmer, Barnabas, et al.
Publicado: (2023)

A pro-apoptotic function of iASPP by stabilizing p300 and CBP through inhibition of BRMS1 E3 ubiquitin ligase activity
por: Kramer, D, et al.
Publicado: (2015)

Functional diversity of microglia – how heterogeneous are they to begin with?
por: Hanisch, Uwe-Karsten
Publicado: (2013)

Higher mortality and impaired elimination of bacteria in aged mice after intracerebral infection with E. coli are associated with an age-related decline of microglia and macrophage functions
por: Schütze, Sandra, et al.
Publicado: (2014)

Hydatid cyst of the liver invading the inferior vena cava
por: Laasri, Khadija, et al.
Publicado: (2023)

R-Based Software for the Integration of Pathway Data into Bioinformatic Algorithms
por: Kramer, Frank, et al.
Publicado: (2014)

Invaders on the Wing
por: Clout, Mick N.
Publicado: (2010)

Exposing the invader
por: Bayer, Avraham N, et al.
Publicado: (2022)

Clinical benefit and cost-effectiveness analysis of liquid biopsy application in patients with advanced non-small cell lung cancer (NSCLC): a modelling approach
por: Englmeier, Fabienne, et al.
Publicado: (2022)

Microglial diversity by responses and responders
por: Gertig, Ulla, et al.
Publicado: (2014)

High-Throughput Profiling of Colorectal Cancer Liver Metastases Reveals Intra- and Inter-Patient Heterogeneity in the EGFR and WNT Pathways Associated with Clinical Outcome
por: Menck, Kerstin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ppkc0jbc36mrmt7lmhfvgjho4t