Arming a Replicating Adenovirus with Osteoprotegerin Reduces the Tumor Burden in a Murine Model of Osteolytic Bone Metastases of Breast Cancer

Most patients with advanced breast cancer develop osteolytic bone metastases, which have numerous complications. Because current therapies are not curative, new treatments are needed. Conditionally replicating adenoviruses (CRAds) are anticancer agents designed to infect and lyse tumor cells. Howeve...

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Detalles Bibliográficos
Autores principales: Cody, James J., Rivera, Angel A., Lyons, Gray R., Yang, Sherry W., Wang, Minghui, Sarver, David B., Wang, Dezhi, Selander, Katri S., Kuo, Hui-Chien, Meleth, Sreelatha, Feng, Xu, Siegal, Gene P., Douglas, Joanne T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842170/
https://www.ncbi.nlm.nih.gov/pubmed/20798695
http://dx.doi.org/10.1038/cgt.2010.47

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