Cargando…

Myc inhibition impairs autophagosome formation

Autophagy, a major clearance route for many long-lived proteins and organelles, has long been implicated in cancer development. Myc is a proto-oncogene often found to be deregulated in many cancers, and thus is an attractive target for design of cancer therapy. Therefore, understanding the relations...

Descripción completa

Detalles Bibliográficos
Autores principales: Toh, Pearl P. C., Luo, Shouqing, Menzies, Fiona M., Raskó, Tamás, Wanker, Erich E., Rubinsztein, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842180/
https://www.ncbi.nlm.nih.gov/pubmed/23933736
http://dx.doi.org/10.1093/hmg/ddt381