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Myc inhibition impairs autophagosome formation
Autophagy, a major clearance route for many long-lived proteins and organelles, has long been implicated in cancer development. Myc is a proto-oncogene often found to be deregulated in many cancers, and thus is an attractive target for design of cancer therapy. Therefore, understanding the relations...
Autores principales: | Toh, Pearl P. C., Luo, Shouqing, Menzies, Fiona M., Raskó, Tamás, Wanker, Erich E., Rubinsztein, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842180/ https://www.ncbi.nlm.nih.gov/pubmed/23933736 http://dx.doi.org/10.1093/hmg/ddt381 |
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