Paradoxical Regulation of Hypoxia Inducible Factor-1α (HIF-1α) by Histone Deacetylase Inhibitor in Diffuse Large B-Cell Lymphoma

Hypoxia inducible factor (HIF) is important in cancer, as it regulates various oncogenic genes as well as genes involved in cell survival, proliferation, and migration. Elevated HIF-1 protein promotes a more aggressive tumor phenotype, and greater HIF-1 expression has been demonstrated to correlate...

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Detalles Bibliográficos
Autores principales: Bhalla, Savita, Evens, Andrew M., Prachand, Sheila, Schumacker, Paul T., Gordon, Leo I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842257/
https://www.ncbi.nlm.nih.gov/pubmed/24312289
http://dx.doi.org/10.1371/journal.pone.0081333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842257/
https://www.ncbi.nlm.nih.gov/pubmed/24312289
http://dx.doi.org/10.1371/journal.pone.0081333

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