A Novel Pulse-Chase SILAC Strategy Measures Changes in Protein Decay and Synthesis Rates Induced by Perturbation of Proteostasis with an Hsp90 Inhibitor

Standard proteomics methods allow the relative quantitation of levels of thousands of proteins in two or more samples. While such methods are invaluable for defining the variations in protein concentrations which follow the perturbation of a biological system, they do not offer information on the me...

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Detalles Bibliográficos
Autores principales: Fierro-Monti, Ivo, Racle, Julien, Hernandez, Celine, Waridel, Patrice, Hatzimanikatis, Vassily, Quadroni, Manfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842330/
https://www.ncbi.nlm.nih.gov/pubmed/24312217
http://dx.doi.org/10.1371/journal.pone.0080423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842330/
https://www.ncbi.nlm.nih.gov/pubmed/24312217
http://dx.doi.org/10.1371/journal.pone.0080423

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