A Cell Permeable Peptide Targeting the Intracellular Loop 2 of Endothelin B Receptor Reduces Pulmonary Hypertension in a Hypoxic Rat Model

Cell permeable peptides (CPP) aid cellular uptake of targeted cargo across the hydrophobic plasma membrane. CPP-mediated cargo delivery of receptor signaling motifs provides an opportunity to regulate specific receptor initiated signaling cascades. Both endothelin-1 receptors, ETA and ETB, have been...

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Detalles Bibliográficos
Autores principales: Green, Daniel S., Rupasinghe, Chamila, Warburton, Rod, Wilson, Jamie L., Sallum, Christine O., Taylor, Linda, Yatawara, Achani, Mierke, Dale, Polgar, Peter, Hill, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842336/
https://www.ncbi.nlm.nih.gov/pubmed/24312288
http://dx.doi.org/10.1371/journal.pone.0081309

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