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Effect of 2-Chloro-Substitution of Adenine Moiety in Mixed-Ligand Gold(I) Triphenylphosphine Complexes on Anti-Inflammatory Activity: The Discrepancy between the In Vivo and In Vitro Models

A series of gold(I) triphenylphosphine (PPh(3)) complexes (1–9) involving 2-chloro-N6-(substituted-benzyl)adenine derivatives as N-donor ligands was synthesized and thoroughly characterized by relevant methods, including electrospray-ionization (ESI) mass spectrometry and multinuclear NMR spectrosco...

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Detalles Bibliográficos
Autores principales: Hošek, Jan, Vančo, Ján, Štarha, Pavel, Paráková, Lenka, Trávníček, Zdeněk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842384/
https://www.ncbi.nlm.nih.gov/pubmed/24312423
http://dx.doi.org/10.1371/journal.pone.0082441

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