Sustained protection against Ebola virus infection following treatment of infected nonhuman primates with ZMAb

Ebola virus (EBOV) is one of the most lethal filoviruses, with mortality rates of up to 90% in humans. Previously, we demonstrated 100% and 50% survival of EBOV-infected cynomologus macaques with a combination of 3 EBOV-GP-specific monoclonal antibodies (ZMAb) administered at 24 or 48 hours post-exp...

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Detalles Bibliográficos
Autores principales: Qiu, Xiangguo, Audet, Jonathan, Wong, Gary, Fernando, Lisa, Bello, Alexander, Pillet, Stéphane, Alimonti, Judie B., Kobinger, Gary P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842534/
https://www.ncbi.nlm.nih.gov/pubmed/24284388
http://dx.doi.org/10.1038/srep03365

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