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Glibenclamide reduces pro-inflammatory cytokine production by neutrophils of diabetes patients in response to bacterial infection

Type 2 diabetes mellitus is a major risk factor for melioidosis, which is caused by Burkholderia pseudomallei. Our previous study has shown that polymorphonuclear neutrophils (PMNs) from diabetic subjects exhibited decreased functions in response to B. pseudomallei. Here we investigated the mechanis...

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Detalles Bibliográficos
Autores principales: Kewcharoenwong, Chidchamai, Rinchai, Darawan, Utispan, Kusumawadee, Suwannasaen, Duangchan, Bancroft, Gregory J., Ato, Manabu, Lertmemongkolchai, Ganjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842541/
https://www.ncbi.nlm.nih.gov/pubmed/24285369
http://dx.doi.org/10.1038/srep03363