Non-structural protein-1 is required for West Nile virus replication complex formation and viral RNA synthesis

BACKGROUND: Flavivirus NS1 is a non-structural glycoprotein that is expressed on the cell surface and secreted into the extracellular space, where it acts as an antagonist of complement pathway activation. Despite its transit through the secretory pathway and intracellular localization in the lumen...

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Detalles Bibliográficos
Autores principales: Youn, Soonjeon, Ambrose, Rebecca L, Mackenzie, Jason M, Diamond, Michael S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842638/
https://www.ncbi.nlm.nih.gov/pubmed/24245822
http://dx.doi.org/10.1186/1743-422X-10-339

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