Main considerable factors for correct laboratory test interpretation under DOA treatment

SUMMARY: To avoid misinterpretation and mismanagement clinicians should be aware of the interference of new direct oral anticoagulants (DOA) on coagulation assays. A variety of oral anticoagulants targeting specific coagulation factors has already entered the market, and new indications for DOA will...

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Detalles Bibliográficos
Autores principales: Mani, Helen, Lindhoff-Last, Edelgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842690/
https://www.ncbi.nlm.nih.gov/pubmed/24176012
http://dx.doi.org/10.1186/1477-9560-11-22
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author Mani, Helen
Lindhoff-Last, Edelgard
author_facet Mani, Helen
Lindhoff-Last, Edelgard
author_sort Mani, Helen
collection PubMed
description SUMMARY: To avoid misinterpretation and mismanagement clinicians should be aware of the interference of new direct oral anticoagulants (DOA) on coagulation assays. A variety of oral anticoagulants targeting specific coagulation factors has already entered the market, and new indications for DOA will be released each year over the next few years. Due to their heterogeneous mode of action and different pharmacokinetic profile each DOA will vary in its effects on coagulations assays, and it is of current importance to recognize these variable effects. In this summary the main considerable factors for correct laboratory test interpretation under DOA treatment are described.
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spelling pubmed-38426902013-11-29 Main considerable factors for correct laboratory test interpretation under DOA treatment Mani, Helen Lindhoff-Last, Edelgard Thromb J Review SUMMARY: To avoid misinterpretation and mismanagement clinicians should be aware of the interference of new direct oral anticoagulants (DOA) on coagulation assays. A variety of oral anticoagulants targeting specific coagulation factors has already entered the market, and new indications for DOA will be released each year over the next few years. Due to their heterogeneous mode of action and different pharmacokinetic profile each DOA will vary in its effects on coagulations assays, and it is of current importance to recognize these variable effects. In this summary the main considerable factors for correct laboratory test interpretation under DOA treatment are described. BioMed Central 2013-11-01 /pmc/articles/PMC3842690/ /pubmed/24176012 http://dx.doi.org/10.1186/1477-9560-11-22 Text en Copyright © 2013 Mani and Lindhoff-Last; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Mani, Helen
Lindhoff-Last, Edelgard
Main considerable factors for correct laboratory test interpretation under DOA treatment
title Main considerable factors for correct laboratory test interpretation under DOA treatment
title_full Main considerable factors for correct laboratory test interpretation under DOA treatment
title_fullStr Main considerable factors for correct laboratory test interpretation under DOA treatment
title_full_unstemmed Main considerable factors for correct laboratory test interpretation under DOA treatment
title_short Main considerable factors for correct laboratory test interpretation under DOA treatment
title_sort main considerable factors for correct laboratory test interpretation under doa treatment
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842690/
https://www.ncbi.nlm.nih.gov/pubmed/24176012
http://dx.doi.org/10.1186/1477-9560-11-22
work_keys_str_mv AT manihelen mainconsiderablefactorsforcorrectlaboratorytestinterpretationunderdoatreatment
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