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Bilateral Putaminal Hemorrhages: Serious Complication of Methanol Intoxication

CONTEXT: Methanol intoxication is a life-threatening condition. Hallmark of clinical presentations include severe wide anion gap metabolic acidosis with very high serum osmolar gap and visual complication. CASE REPORT: We report a case of severe methanol intoxication with bilateral putaminal hemorrh...

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Autores principales: Permpalung, Nitipong, Cheungpasitporn, Wisit, Chongnarungsin, Daych, Hodgdon, Travis M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842708/
https://www.ncbi.nlm.nih.gov/pubmed/24350079
http://dx.doi.org/10.4103/1947-2714.120804
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author Permpalung, Nitipong
Cheungpasitporn, Wisit
Chongnarungsin, Daych
Hodgdon, Travis M
author_facet Permpalung, Nitipong
Cheungpasitporn, Wisit
Chongnarungsin, Daych
Hodgdon, Travis M
author_sort Permpalung, Nitipong
collection PubMed
description CONTEXT: Methanol intoxication is a life-threatening condition. Hallmark of clinical presentations include severe wide anion gap metabolic acidosis with very high serum osmolar gap and visual complication. CASE REPORT: We report a case of severe methanol intoxication with bilateral putaminal hemorrhage, an uncommon serious complication. A 56-year-old man presented with altered mental status. Fundus examination showed optic disc edema. Arterial Blood Gas (ABG) revealed severe anion gap metabolic acidosis with osmolal gap. Head computed tomography (CT) showed hypodense lesions in basal ganglia bilaterally. Hemodialysis and intravenous fomepizole were initiated. Serum methanol level was significantly elevated. Unfortunately, patient was lethargic 2 weeks after discharge. Repeated CT of head demonstrated new putaminal hemorrhages. CONCLUSION: Bilateral putaminal hemorrhage is an uncommon but serious complication in methanol intoxication. Clinicians should have high index of suspicion for putaminal hemorrhage when patients with recent methanol intoxication present with altered mental status.
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spelling pubmed-38427082013-12-13 Bilateral Putaminal Hemorrhages: Serious Complication of Methanol Intoxication Permpalung, Nitipong Cheungpasitporn, Wisit Chongnarungsin, Daych Hodgdon, Travis M N Am J Med Sci Case Report CONTEXT: Methanol intoxication is a life-threatening condition. Hallmark of clinical presentations include severe wide anion gap metabolic acidosis with very high serum osmolar gap and visual complication. CASE REPORT: We report a case of severe methanol intoxication with bilateral putaminal hemorrhage, an uncommon serious complication. A 56-year-old man presented with altered mental status. Fundus examination showed optic disc edema. Arterial Blood Gas (ABG) revealed severe anion gap metabolic acidosis with osmolal gap. Head computed tomography (CT) showed hypodense lesions in basal ganglia bilaterally. Hemodialysis and intravenous fomepizole were initiated. Serum methanol level was significantly elevated. Unfortunately, patient was lethargic 2 weeks after discharge. Repeated CT of head demonstrated new putaminal hemorrhages. CONCLUSION: Bilateral putaminal hemorrhage is an uncommon but serious complication in methanol intoxication. Clinicians should have high index of suspicion for putaminal hemorrhage when patients with recent methanol intoxication present with altered mental status. Medknow Publications & Media Pvt Ltd 2013-10 /pmc/articles/PMC3842708/ /pubmed/24350079 http://dx.doi.org/10.4103/1947-2714.120804 Text en Copyright: © North American Journal of Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Permpalung, Nitipong
Cheungpasitporn, Wisit
Chongnarungsin, Daych
Hodgdon, Travis M
Bilateral Putaminal Hemorrhages: Serious Complication of Methanol Intoxication
title Bilateral Putaminal Hemorrhages: Serious Complication of Methanol Intoxication
title_full Bilateral Putaminal Hemorrhages: Serious Complication of Methanol Intoxication
title_fullStr Bilateral Putaminal Hemorrhages: Serious Complication of Methanol Intoxication
title_full_unstemmed Bilateral Putaminal Hemorrhages: Serious Complication of Methanol Intoxication
title_short Bilateral Putaminal Hemorrhages: Serious Complication of Methanol Intoxication
title_sort bilateral putaminal hemorrhages: serious complication of methanol intoxication
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842708/
https://www.ncbi.nlm.nih.gov/pubmed/24350079
http://dx.doi.org/10.4103/1947-2714.120804
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