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Bilateral Putaminal Hemorrhages: Serious Complication of Methanol Intoxication
CONTEXT: Methanol intoxication is a life-threatening condition. Hallmark of clinical presentations include severe wide anion gap metabolic acidosis with very high serum osmolar gap and visual complication. CASE REPORT: We report a case of severe methanol intoxication with bilateral putaminal hemorrh...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842708/ https://www.ncbi.nlm.nih.gov/pubmed/24350079 http://dx.doi.org/10.4103/1947-2714.120804 |
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author | Permpalung, Nitipong Cheungpasitporn, Wisit Chongnarungsin, Daych Hodgdon, Travis M |
author_facet | Permpalung, Nitipong Cheungpasitporn, Wisit Chongnarungsin, Daych Hodgdon, Travis M |
author_sort | Permpalung, Nitipong |
collection | PubMed |
description | CONTEXT: Methanol intoxication is a life-threatening condition. Hallmark of clinical presentations include severe wide anion gap metabolic acidosis with very high serum osmolar gap and visual complication. CASE REPORT: We report a case of severe methanol intoxication with bilateral putaminal hemorrhage, an uncommon serious complication. A 56-year-old man presented with altered mental status. Fundus examination showed optic disc edema. Arterial Blood Gas (ABG) revealed severe anion gap metabolic acidosis with osmolal gap. Head computed tomography (CT) showed hypodense lesions in basal ganglia bilaterally. Hemodialysis and intravenous fomepizole were initiated. Serum methanol level was significantly elevated. Unfortunately, patient was lethargic 2 weeks after discharge. Repeated CT of head demonstrated new putaminal hemorrhages. CONCLUSION: Bilateral putaminal hemorrhage is an uncommon but serious complication in methanol intoxication. Clinicians should have high index of suspicion for putaminal hemorrhage when patients with recent methanol intoxication present with altered mental status. |
format | Online Article Text |
id | pubmed-3842708 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-38427082013-12-13 Bilateral Putaminal Hemorrhages: Serious Complication of Methanol Intoxication Permpalung, Nitipong Cheungpasitporn, Wisit Chongnarungsin, Daych Hodgdon, Travis M N Am J Med Sci Case Report CONTEXT: Methanol intoxication is a life-threatening condition. Hallmark of clinical presentations include severe wide anion gap metabolic acidosis with very high serum osmolar gap and visual complication. CASE REPORT: We report a case of severe methanol intoxication with bilateral putaminal hemorrhage, an uncommon serious complication. A 56-year-old man presented with altered mental status. Fundus examination showed optic disc edema. Arterial Blood Gas (ABG) revealed severe anion gap metabolic acidosis with osmolal gap. Head computed tomography (CT) showed hypodense lesions in basal ganglia bilaterally. Hemodialysis and intravenous fomepizole were initiated. Serum methanol level was significantly elevated. Unfortunately, patient was lethargic 2 weeks after discharge. Repeated CT of head demonstrated new putaminal hemorrhages. CONCLUSION: Bilateral putaminal hemorrhage is an uncommon but serious complication in methanol intoxication. Clinicians should have high index of suspicion for putaminal hemorrhage when patients with recent methanol intoxication present with altered mental status. Medknow Publications & Media Pvt Ltd 2013-10 /pmc/articles/PMC3842708/ /pubmed/24350079 http://dx.doi.org/10.4103/1947-2714.120804 Text en Copyright: © North American Journal of Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Permpalung, Nitipong Cheungpasitporn, Wisit Chongnarungsin, Daych Hodgdon, Travis M Bilateral Putaminal Hemorrhages: Serious Complication of Methanol Intoxication |
title | Bilateral Putaminal Hemorrhages: Serious Complication of Methanol Intoxication |
title_full | Bilateral Putaminal Hemorrhages: Serious Complication of Methanol Intoxication |
title_fullStr | Bilateral Putaminal Hemorrhages: Serious Complication of Methanol Intoxication |
title_full_unstemmed | Bilateral Putaminal Hemorrhages: Serious Complication of Methanol Intoxication |
title_short | Bilateral Putaminal Hemorrhages: Serious Complication of Methanol Intoxication |
title_sort | bilateral putaminal hemorrhages: serious complication of methanol intoxication |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842708/ https://www.ncbi.nlm.nih.gov/pubmed/24350079 http://dx.doi.org/10.4103/1947-2714.120804 |
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