Optimal sampling designs for estimation of Plasmodium falciparum clearance rates in patients treated with artemisinin derivatives

BACKGROUND: The emergence of Plasmodium falciparum resistance to artemisinins in Southeast Asia threatens the control of malaria worldwide. The pharmacodynamic hallmark of artemisinin derivatives is rapid parasite clearance (a short parasite half-life), therefore, the in vivo phenotype of slow clear...

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Detalles Bibliográficos
Autores principales: Flegg, Jennifer A, Guérin, Philippe J, Nosten, Francois, Ashley, Elizabeth A, Phyo, Aung Pyae, Dondorp, Arjen M, Fairhurst, Rick M, Socheat, Duong, Borrmann, Steffen, Björkman, Anders, Mårtensson, Andreas, Mayxay, Mayfong, Newton, Paul N, Bethell, Delia, Se, Youry, Noedl, Harald, Diakite, Mahamadou, Djimde, Abdoulaye A, Hien, Tran T, White, Nicholas J, Stepniewska, Kasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842737/
https://www.ncbi.nlm.nih.gov/pubmed/24225303
http://dx.doi.org/10.1186/1475-2875-12-411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842737/
https://www.ncbi.nlm.nih.gov/pubmed/24225303
http://dx.doi.org/10.1186/1475-2875-12-411

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