Cargando…

Fast in vitro methods to determine the speed of action and the stage-specificity of anti-malarials in Plasmodium falciparum

BACKGROUND: Recent whole cell in vitro screening campaigns identified thousands of compounds that are active against asexual blood stages of Plasmodium falciparum at submicromolar concentrations. These hits have been made available to the public, providing many novel chemical starting points for ant...

Descripción completa

Detalles Bibliográficos
Autores principales:	Le Manach, Claire, Scheurer, Christian, Sax, Sibylle, Schleiferböck, Sarah, Cabrera, Diego Gonzalez, Younis, Yassir, Paquet, Tanya, Street, Leslie, Smith, Peter, Ding, Xavier C, Waterson, David, Witty, Michael J, Leroy, Didier, Chibale, Kelly, Wittlin, Sergio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842807/ https://www.ncbi.nlm.nih.gov/pubmed/24237770 http://dx.doi.org/10.1186/1475-2875-12-424

Ejemplares similares

Identification of Plasmodium PI4 kinase as target of MMV390048 by chemoproteomics
por: Ghidelli-Disse, Sonja, et al.
Publicado: (2014)

Anti-malarial drugs: how effective are they against Plasmodium falciparum gametocytes?
por: Peatey, Christopher L, et al.
Publicado: (2012)

In vitro interaction of artemisinin derivatives or the fully synthetic peroxidic anti-malarial OZ277 with thapsigargin in Plasmodium falciparum strains
por: Abiodun, Oyindamola O, et al.
Publicado: (2013)

A new double-antibody sandwich ELISA targeting Plasmodium falciparum aldolase to evaluate anti-malarial drug sensitivity
por: Tritten, Lucienne, et al.
Publicado: (2009)

The Parasite Reduction Ratio (PRR) Assay Version 2: Standardized Assessment of Plasmodium falciparum Viability after Antimalarial Treatment In Vitro
por: Walz, Annabelle, et al.
Publicado: (2023)

THE CULTIVATION OF MALARIAL PLASMODIA (PLASMODIUM VIVAX AND PLASMODIUM FALCIPARUM) IN VITRO
por: Bass, C. C., et al.
Publicado: (1912)

Risk factors for Plasmodium falciparum hyperparasitaemia in malarious children
por: Sowunmi, Akintunde, et al.
Publicado: (2011)

Isothermal Microcalorimetry, a New Tool to Monitor Drug Action against Trypanosoma brucei and Plasmodium falciparum
por: Wenzler, Tanja, et al.
Publicado: (2012)

Systems Analysis of Chaperone Networks in the Malarial Parasite Plasmodium falciparum
por: Pavithra, Soundara Raghavan, et al.
Publicado: (2007)

The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis
por: Hitz, Eva, et al.
Publicado: (2021)

Evidence for differences in erythrocyte surface receptors for the malarial parasites, Plasmodium falciparum and Plasmodium knowlesi
Publicado: (1977)

In vitro and in vivo characterization of the antimalarial lead compound SSJ-183 in Plasmodium models
por: Schleiferböck, Sarah, et al.
Publicado: (2013)

Modulating effects of plasma containing anti-malarial antibodies on in vitro anti-malarial drug susceptibility in Plasmodium falciparum
por: Monatrakul, Preeyaporn, et al.
Publicado: (2010)

In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate
por: Baumgärtner, Fabian, et al.
Publicado: (2017)

Screening a protein kinase inhibitor library against Plasmodium falciparum
por: Hallyburton, Irene, et al.
Publicado: (2017)

Predicting transmission blocking potential of anti-malarial compounds in the Mosquito Feeding Assay using Plasmodium falciparum Male Gamete Inhibition Assay
por: Colmenarejo, Gonzalo, et al.
Publicado: (2018)

Anti-malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring-stage survival assay
por: Walz, Annabelle, et al.
Publicado: (2019)

Crystal structure of the aquaglyceroporin PfAQP from the malarial parasite Plasmodium falciparum
por: Newby, Zachary E R, et al.
Publicado: (2008)

Molecular dynamics simulations of PfAQP from the malarial parasite Plasmodium falciparum
por: CUI, YUBAO, et al.
Publicado: (2012)

Differential Plasmodium falciparum surface antigen expression among children with Malarial Retinopathy
por: Abdi, Abdirahman I., et al.
Publicado: (2015)

The Activities of Current Antimalarial Drugs on the Life Cycle Stages of Plasmodium: A Comparative Study with Human and Rodent Parasites
por: Delves, Michael, et al.
Publicado: (2012)

Plasmodium falciparum parasite population structure and gene flow associated to anti-malarial drugs resistance in Cambodia
por: Dwivedi, Ankit, et al.
Publicado: (2016)

Prevalence of molecular markers of anti-malarial drug resistance in Plasmodium vivax and Plasmodium falciparum in two districts of Nepal
por: Ranjitkar, Samir, et al.
Publicado: (2011)

Maintenance of the human malarial parasite, Plasmodium falciparum, in scid mice and transmission of gametocytes to mosquitoes
Publicado: (1995)

Global gene expression profiling of Plasmodium falciparum in response to the anti-malarial drug pyronaridine
por: Kritsiriwuthinan, Kanyanan, et al.
Publicado: (2011)

Intracytoplasmic Hemozoin (Malarial Pigment) in a Case of Severe, Aparasitemic Plasmodium falciparum Malaria
por: Grande, Romualdo, et al.
Publicado: (2011)

Homopolymer tract organization in the human malarial parasite Plasmodium falciparum and related Apicomplexan parasites
por: Russell, Karen, et al.
Publicado: (2014)

Profiling of the anti-malarial drug candidate SC83288 against artemisinins in Plasmodium falciparum
por: Duffey, Maëlle, et al.
Publicado: (2018)

Plasmodium vivax and Plasmodium falciparum ex vivo susceptibility to anti-malarials and gene characterization in Rondônia, West Amazon, Brazil
por: Aguiar, Anna Caroline C, et al.
Publicado: (2014)

Identification of a strain-specific malarial antigen exposed on the surface of Plasmodium falciparum-infected erythrocytes
Publicado: (1984)

Involvement of spectrin and ATP in infection of resealed erythrocyte ghosts by the human malarial parasite, Plasmodium falciparum
Publicado: (1982)

Human saliva as a source of anti-malarial antibodies to examine population exposure to Plasmodium falciparum
por: Estévez, Patricia Tabernero, et al.
Publicado: (2011)

A comprehensive survey of polymorphisms conferring anti-malarial resistance in Plasmodium falciparum across Pakistan
por: Khattak, Aamer A, et al.
Publicado: (2013)

Malarial parasite diversity in chimpanzees: the value of comparative approaches to ascertain the evolution of Plasmodium falciparum antigens
por: Pacheco, M Andreína, et al.
Publicado: (2013)

In vitro studies on the sensitivity pattern of Plasmodium falciparum to anti-malarial drugs and local herbal extracts
por: Olasehinde, Grace I, et al.
Publicado: (2014)

Effect of mild medical hypothermia on in vitro growth of Plasmodium falciparum and the activity of anti-malarial drugs
por: Rehman, Khalid, et al.
Publicado: (2016)

Molecular surveillance of anti-malarial drug resistance genes in Plasmodium falciparum isolates in Odisha, India
por: Rana, Ramakanta, et al.
Publicado: (2022)

Antibodies in malarial sera to parasite antigens in the membrane of erythrocytes infected with early asexual stages of Plasmodium falciparum
Publicado: (1984)

In vitro activity of pyronaridine against Plasmodium falciparum and comparative evaluation of anti-malarial drug susceptibility assays
por: Kurth, Florian, et al.
Publicado: (2009)

Effects of mefloquine and artesunate mefloquine on the emergence, clearance and sex ratio of Plasmodium falciparum gametocytes in malarious children
por: Sowunmi, Akintunde, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_vd4n0lsshuenscv2kncpg9o3p1