NK cells from an AML patient have recovered in remission and reached comparable cytolytic activity to that of a healthy monozygotic twin mediated by the single-chain triplebody SPM-2

BACKGROUND: The capacity of patient’s Natural Killer cells (NKs) to be activated for cytolysis is an important prerequisite for the success of antibody-derived agents such as single-chain triplebodies (triplebodies) in cancer therapy. NKs recovered from AML patients at diagnosis are often found to b...

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Detalles Bibliográficos
Autores principales: Braciak, Todd A, Wildenhain, Sarah, Roskopf, Claudia C, Schubert, Ingo A, Fey, Georg H, Jacob, Uwe, Hopfner, Karl-Peter, Oduncu, Fuat S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842817/
https://www.ncbi.nlm.nih.gov/pubmed/24237598
http://dx.doi.org/10.1186/1479-5876-11-289

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