Dendritic Cell-Specific Delivery of Flt3L by Coronavirus Vectors Secures Induction of Therapeutic Antitumor Immunity

Efficacy of antitumor vaccination depends to a large extent on antigen targeting to dendritic cells (DCs). Here, we assessed antitumor immunity induced by attenuated coronavirus vectors which exclusively target DCs in vivo and express either lymphocyte- or DC-activating cytokines in combination with...

Descripción completa

Detalles Bibliográficos
Autores principales: Perez-Shibayama, Christian, Gil-Cruz, Cristina, Nussbacher, Monika, Allgäuer, Eva, Cervantes-Barragan, Luisa, Züst, Roland, Ludewig, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842931/
https://www.ncbi.nlm.nih.gov/pubmed/24312302
http://dx.doi.org/10.1371/journal.pone.0081442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842931/
https://www.ncbi.nlm.nih.gov/pubmed/24312302
http://dx.doi.org/10.1371/journal.pone.0081442

Ejemplares similares