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Dendritic Cell-Specific Delivery of Flt3L by Coronavirus Vectors Secures Induction of Therapeutic Antitumor Immunity
Efficacy of antitumor vaccination depends to a large extent on antigen targeting to dendritic cells (DCs). Here, we assessed antitumor immunity induced by attenuated coronavirus vectors which exclusively target DCs in vivo and express either lymphocyte- or DC-activating cytokines in combination with...
Autores principales: | Perez-Shibayama, Christian, Gil-Cruz, Cristina, Nussbacher, Monika, Allgäuer, Eva, Cervantes-Barragan, Luisa, Züst, Roland, Ludewig, Burkhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842931/ https://www.ncbi.nlm.nih.gov/pubmed/24312302 http://dx.doi.org/10.1371/journal.pone.0081442 |
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