C3 glomerulopathy: consensus report

C3 glomerulopathy is a recently introduced pathological entity whose original definition was glomerular pathology characterized by C3 accumulation with absent or scanty immunoglobulin deposition. In August 2012, an invited group of experts (comprising the authors of this document) in renal pathology...

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Detalles Bibliográficos
Autores principales: Pickering, Matthew C, D'Agati, Vivette D, Nester, Carla M, Smith, Richard J, Haas, Mark, Appel, Gerald B, Alpers, Charles E, Bajema, Ingeborg M, Bedrosian, Camille, Braun, Michael, Doyle, Mittie, Fakhouri, Fadi, Fervenza, Fernando C, Fogo, Agnes B, Frémeaux-Bacchi, Véronique, Gale, Daniel P, Goicoechea de Jorge, Elena, Griffin, Gene, Harris, Claire L, Holers, V Michael, Johnson, Sally, Lavin, Peter J, Medjeral-Thomas, Nicholas, Paul Morgan, B, Nast, Cynthia C, Noel, Laure-Hélène, Peters, D Keith, Rodríguez de Córdoba, Santiago, Servais, Aude, Sethi, Sanjeev, Song, Wen-Chao, Tamburini, Paul, Thurman, Joshua M, Zavros, Michael, Cook, H Terence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Meeting Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842953/
https://www.ncbi.nlm.nih.gov/pubmed/24172683
http://dx.doi.org/10.1038/ki.2013.377
Descripción
Sumario:C3 glomerulopathy is a recently introduced pathological entity whose original definition was glomerular pathology characterized by C3 accumulation with absent or scanty immunoglobulin deposition. In August 2012, an invited group of experts (comprising the authors of this document) in renal pathology, nephrology, complement biology, and complement therapeutics met to discuss C3 glomerulopathy in the first C3 Glomerulopathy Meeting. The objectives were to reach a consensus on: the definition of C3 glomerulopathy, appropriate complement investigations that should be performed in these patients, and how complement therapeutics should be explored in the condition. This meeting report represents the current consensus view of the group.

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