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Oral Leptin Treatment in Suckling Rats Ameliorates Detrimental Effects in Hypothalamic Structure and Function Caused by Maternal Caloric Restriction during Gestation

A poor prenatal environment brings about perturbations in leptin surge and hypothalamic circuitry that program impaired ability to regulate energy homeostasis in adulthood. Here, using a rat model of moderate maternal caloric restriction during gestation, we aimed to investigate whether leptin suppl...

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Detalles Bibliográficos
Autores principales: Konieczna, Jadwiga, García, Ana Paula, Sánchez, Juana, Palou, Mariona, Palou, Andreu, Picó, Catalina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842976/
https://www.ncbi.nlm.nih.gov/pubmed/24312379
http://dx.doi.org/10.1371/journal.pone.0081906