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Identification of cell cycle–regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors

We identify the cell cycle–regulated mRNA transcripts genome-wide in the osteosarcoma-derived U2OS cell line. This results in 2140 transcripts mapping to 1871 unique cell cycle–regulated genes that show periodic oscillations across multiple synchronous cell cycles. We identify genomic loci bound by...

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Detalles Bibliográficos
Autores principales: Grant, Gavin D., Brooks, Lionel, Zhang, Xiaoyang, Mahoney, J. Matthew, Martyanov, Viktor, Wood, Tammara A., Sherlock, Gavin, Cheng, Chao, Whitfield, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842991/
https://www.ncbi.nlm.nih.gov/pubmed/24109597
http://dx.doi.org/10.1091/mbc.E13-05-0264